Unit FUNCTIONAL SEMIOLOGY IN VETERINARY INTERNAL MEDICINE

Course
Veterinary medicine
Study-unit Code
85100006
Curriculum
In all curricula
Teacher
Luca Avellini
CFU
6
Course Regulation
Coorte 2015
Offered
2017/18
Type of study-unit
Obbligatorio (Required)
Type of learning activities
Attività formativa integrata

CLINICAL BIOCHEMISTRY

Code 85002203
CFU 3
Teacher Luca Avellini
Teachers
  • Luca Avellini
Hours
  • 42 ore - Luca Avellini
Learning activities Affine/integrativa
Area Attività formative affini o integrative
Academic discipline BIO/12
Type of study-unit Obbligatorio (Required)
Language of instruction Italian
Contents Knowledge necessary to understand the process of production of laboratory data for its critical interpretation. Basic concepts of analytical variability and biological variation, pre-analytical phase, reference values and quality control. Basic concepts of the most used techniques. Point-of-Care testing; Biochemical markers of function or damage of tissues or organs in different animal species.
Reference texts consultazione: S. Paltrinieri, W. Bertazzolo, A. Giordano - Patologia clinica del cane e del gatto. Masson
Meyer D.J. Harvey J.W. - Medicina di laboratorio veterinaria– interpretazione e diagnosi. Delfino Editore
Educational objectives The oral exam certifies the knowledge of the meaning and the interpretation ability of clinical laboratory data. In particular, students have to reach an adequate knowledge and ability to use of the simplest methods for acquisition of laboratory data and understand the contribution that laboratory diagnostic techniques can make in achieving a diagnosis.
Teaching methods The course is organized as follow:

- Lectures (26 hours) on all subjects of the course

- n° 2 laboratory exercises (overall 4 hours) will be done at the teaching lab (basement of the main building) for the knowledge/solution of basic problems regarding clinical chemistry lab. Students will be divided into groups (maximum 20 students per group).
Other information On-line availability of the material used by the teacher for lessons

The teacher becomes available (by prior arrangement) even outside of official office hours (Tues and Thurs 13-14) for explanations about the topics of the program.
Extended program TECNICHE ANALITICHE e QUALITÀ ANALITICA:
Concetti di base sull'attendibilità analitica: precisione, accuratezza, sensibilità e specificità, la gestione della qualità. Il controllo di qualità interno. Valore predittivo e livelli decisionali (4,5 ore).
Grandezze e unità di misura in biochimica clinica, variabilità preanalitica, valori di riferimento e variabilità biologica, concetto di differenza critica e di traguardo di qualità analitica (3 ore).
Principi e tecniche di raccolta, processazione e conservazione dei campioni biologici (1,5 ore).
Concetti di base delle tecniche maggiormente utilizzate in biochimica clinica con particolare riferimento ai principi di base e alle potenzialità applicative delle tecniche enzimatiche (2 ore). Point-of-Care testing e chimica allo stato secco: principi e sua utilizzazione nell'esame delle urine e nel monitoraggio ambulatoriale della glicemia (1 ora). Emogasanalizzatore (1 ora).
MARCATORI dI MALATTIA:
Paramentri biochimici marcatori di funzione e di lesione di tessuto e di organo nelle diverse specie animali con particolare riferimento a: disturbi del metabolismo idro-elettrolitico e acido-base (emogasanalisi) (3 ore), omeostasi glucidica e test dinamici di funzionalità del pancreas endocrino (3 ore); metabolismo dell'eme e ittero e marcatori di funzionalità epatica (2 ore). Biochimica clinica delle encefalopatie spongiformi trasmissibili (2 ore). Enzimologia clinica (1,5 ore). Biochimica clinica dell'esercizio fisico (1,5 ore).
Lezioni Pratiche:
Buona pratica di laboratorio. etichette e schede di sicurezza. Valutazione della precisione di un metodo (2 ore).
Esame delle urine, chimica allo stato secco, applicazione di metodi qualitativi, semiquantitativi e quantitativi per il dosaggio del glucosio (2 ore)

LABORATORY DIAGNOSTIC IN CLINICAL PRACTICE

Code 85107303
CFU 3
Teacher Luca Avellini
Teachers
  • Maria Teresa Antognoni (Codocenza)
Hours
  • 39 ore (Codocenza) - Maria Teresa Antognoni
Learning activities Caratterizzante
Area Discipline cliniche veterinarie
Academic discipline VET/08
Type of study-unit Obbligatorio (Required)
Language of instruction Italian
Contents Interpretation of different laboratory parameters in relation to the functionality of the organ.

General laboratory concepts:sources of laboratory error; preanalytical errors: hemolysis, lipemia, icterus. Analitical errors. Sample collection. Metabolic profile.
Serum total protein. Protein electrophoresis; Altered electrophoretic patterns; Acute fase proteinsHyperglobulinemia, hypoglobulinemia, monoclonal gammopathy.
Hepatic disorders. Nefrology disorders. Urynary disorders.
Hemostatic abnormalities.
Fluid accumulation disorders: diagnostic approach, fluid collection technique, characterization of fluid. Gastrointestinal and pancreatic disorders. Cardiac disorders. Endocrine disorders
Reference texts notes from teacher

Testi di consultazione: S. Paltrinieri, W. Bertazzolo, A. Giordano - Patologia clinica del cane e del gatto. Masson

Meyer D.J. Harvey J.W. - Medicina di laboratorio veterinaria– interpretazione e diagnosi. Delfino Editore

Michael D., Willard - Smal animal Clinical diagnosis by laboratory methods. Fifth edition. Elsevier
Educational objectives The main goal of education is to provide students with the foundation to address the study and knowledge of the main laboratory parameters are designed to veil diseases of organ and to learn to grasp the clinical significance in relation to various diseases.

The main skills are:

knowledge about the sampling procedure and storage of various materials

knowledge related to laboratory parameters such as markers of organ function, in different animal species

The main skills are:

perform surveys in specialized laboratories

analyze the data coming from the different samples

interpret data to identify diseases of organ and to address a differential diagnosis
Prerequisites NO
Teaching methods Theoretical lessons and practical training
Other information NO
Extended program General laboratory concepts:sources of laboratory error; preanalytical errors: hemolysis, lipemia, icterus. Analitical errors. Sample collection. Metabolic profile.
Serum total protein. Protein electrophoresis; Altered electrophoretic patterns; Acute fase proteinsHyperglobulinemia, hypoglobulinemia, monoclonal gammopathy.
Hepatic disorders. Nefrology disorders. Urynary disorders.
Hemostatic abnormalities.
Fluid accumulation disorders: diagnostic approach, fluid collection technique, characterization of fluid. Gastrointestinal and pancreatic disorders. Cardiac disorders. Endocrine disorders
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